PEMCRC Research Output

PEMCRC Projects & Publications

Inception DateProjectPrincipal Investigator(s) & Mentor(s)FundingPublications
Winter 2017Acute Otitis Media in the Newborn periodMcLaren S, Cruz AT, Dayan PNoneStudy Start-up 2017.12
Winter 2017Submersion score & outcomes in ChildrenShenoi RNoneStudy start-up 2017.10
Summer 2017Outcomes and care patterns for neonatal Omphalitis & MastitisKaplan R, Bajaj LNoneCollaborative agreements initiated 2017.12
Summer 2016PEM Fellows & Research CareeresMichelson K, Mistry RNoneMichelson KA, Nigrovic LE, Nagler J, McAneney CM, Mistry RD for the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC). Research Interest in Pediatric Emergency Medicine Fellows and Recent Graduates. Pediatr Emerg Car. Published online March 13, 2017.
Fall 2015Hemolytic-Uremic SyndromeMcKee R, Schnadower DNoneData collection ongoing
Spring 2015Fusobacterium Bacteremia Curfman A, Schnadower DNoneCurfman, Burnham, Hayes, Schnadower for the PEMCRC Fusobacterium study group: Pediatric Anaerobic Blood Culture Practices in Developed Countries. Poster presentation at PAS 2016 (Baltimore, MD).
Fall 2013Herpes Simplex Virus in infantsCruz AT, Freedman S, Nigrovic LENoneCruz A, Freedman S, Kulik D, Fleming A, Thomson J, Schnadower D, Garro A, Pruitt C, Balamuth F, Aronson P, Uspal N, Lyons T, Ishimine P, Bradin S, Grether-Jones K, Miller A, Louie L, Shah S, Nigrovic L for the Pediatric Emergency Medicine Collaborative Research Committee (PEM-CRC) HSV Study Group. HSV in infants <= 60 days presenting for emergency department evaluation. Pediatrics. Published online February 5, 2018.
Lyons TW, Cruz AT, Freedman SB, Numen MI, Balamuth F, Mistry R, Mahajan P, Aronson PL, Thomson JE, Pruitt CM, Shah SS, Nigrovic LE for the Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus (HSV) Study Group. Interpretation of cerebrospinal fluid white blood cell counts in young infants with a traumatic lumbar puncture. Ann Emerg Med. 2017; 69(5):622-31.
Thomson J, Cruz AT, Nigrovic LE, Freedman SB, Garro AC, Ishimine PT, Kulik DM, Uspal NG, Grether-Jones KL, Miller AS, Schnadower D, Shah SS, for the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC) HSV Study Group. Concomitant Bacterial Meningitis in Infants with Urinary Tract Infection. Pediatr Infect Dis J. 2017; 36(9):908-10.
Lyons TW, Cruz AT, Freedman SB, Arms JL, Aronson PL, Fleming AH, Kulik D, Mahajan P, Mistry RD, Pruitt CM, Thompson AD, Nigrovic LE for the Pediatric Emergency Care Collaborative Research Committee (PEM CRC). Correction of cerebrospinal fluid protein in infants with a traumatic lumbar puncture. Pediatr Infec Dis J. 2017;36 (10):1006-1008.
Aronson PL, Lyons TW, Cruz AT, Freedman SB, Okada PJ, Fleming AH, Arms JL, Thompson AD, Schmidt SM, Louie J, Alfonzo MJ, Schnadower D, Monuteaux MC, Nigrovic LE for the Pediatric Emergency Care Collaborative Research Committee (PEM CRC). Impact of cerebrospinal enteroviral testing on length of stay for hospitalized infants ≤ 60 days. J Pediatr. 2017;189:169-174.
Thomson J, Sucharew H, Cruz AT, Nigrovic LE, Freedman SB, Garro AC, Balamuth F, Mistry RD, Arms JL, Ishimine PT, Kulik DM, Neuman MI, Shah SS. Cerebrospinal Fluid Reference Values for Young Infants Undergoing Lumbar Puncture. Pediatrics. 2017 in press.
Cruz AT, Nigrovic LE, Freedman SB, Okada PJ, Grether-Jones KL, Aronson PL, Fleming AH, Louie J, Schmidt, Pruitt CM, Uspal NG, Mahajan P for the Pediatric Emergency Care Collaborative Research Committee (PEM CRC). Frequency of Contaminants in Bacterial Cultures of Infants 0-60 Days of Age. Poster presentation at PAS 2017 (San Francisco, CA).
2009Urinary Tract InfectionsSchnadower D, Dayan P, Kuppermann NNone-Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS; American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee. Febrile infants with urinary tract infections at very low risk for adverse events and bacteremia. Pediatrics. 2010;126(6):1074-83.
-Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS; Sterile cerebrospinal fluid pleocytosis in young febrile infants with urinary tract infections. Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Arch Pediatr Adolesc Med. 2011;165(7):635-41.
-Schnadower D, Kuppermann N, Macias CG, Freedman SB, Agrawal D, Mao J, Dayan PS for the American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee UTI Study Group. Outpatient management of young febrile infants with urinary tract infections. Pediatr Emerg Care. 2014 Sep;30(9):591-7.
-Lubell, Schnadower, Kuppermann, Agrawal, Freedman, Dayan for the PEMCRC UTI study group: Comparison of Febrile Infants with Enterococcal and Gram-Negative Urinary Tract Infections. Pediatr Infecti Dis J. 2016. 35(9):943-8.
2009AppendicitisKharbanda A, Dayan PColumbia University $10,000-Kharbanda AB, Stevenson MD, Macias CG, Sinclair K, Dudley NC, Bennett J, Bajaj L, Mittal MK, Huang C, Bachur RG, Dayan PS; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Interrater reliability of clinical findings in children with possible appendicitis. Pediatrics. 2012;129(4):695-700.
Bachur RG, Dayan PS, Bajaj L, Macias CG, Mittal MK, Stevenson MD, Dudley NC, Sinclair K, Bennett J, Monuteaux MC, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. The effect of abdominal pain duration on the accuracy of diagnostic imaging for pediatric appendicitis. Ann Emerg Med. 2012;60(5):582-590.
Kharbanda AB, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bachur RG, Bennett JE, Sinclair K, Huang C, Dayan PS; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Validation and refinement of a prediction rule to identify children at low risk for acute appendicitis. Arch Pediatr Adolesc Med. 2012;166(8):738-44.
Mittal MK, Dayan PS, Macias CG, Bachur RG, Bennett J, Dudley NC, Bajaj L, Sinclair K, Stevenson MD, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Performance of ultrasound in the diagnosis of appendicitis in children in a multicenter cohort. Acad Emerg Med. 2013;20(7):697-702.
Levas MN, Dayan PS, Mittal MK, Stevenson MD, Bachur RG, Dudley NC, Bajaj L, Macias CG, Bennett J, Dowd MD, Thomas AJ, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Effect of Hispanic ethnicity and language barriers on appendiceal perforation rates and imaging in children. J Pediatr. 2014;164(6):1286-91.
Bachur RG, Dayan PS, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bennett J, Sinclair K, Monuteaux MC, Kharbanda AB. The Influence of Age on the Diagnostic Performance of White Blood Cell Count and Absolute Neutrophil Count in Suspected Pediatric Appendicitis. Acad Emerg Med. 2016; 23(11):1235-42
Kharbanda AB, Monuteaux MC, Bachur RG, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bennett JE, Sinclair K, Dayan PS for Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. A clinical score to predict appendicitis in older male children. Acad Pediatr. 2017; 17(3):261-6.
MeningitisNigrovic LE, Kuppermann N, Malley RAcademic Pediatric Association $10,000-Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kanegaye JT, Malley R; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007;297(1):52-60.
-Nigrovic LE, Kuppermann N, Malley R; Bacterial Meningitis Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era. Acad Emerg Med. 2008;15(6):522-8.
-Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee. Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis. Pediatrics. 2008;122(4):726-30.
-Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee.; Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009;123(6):e967-71.
-Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee. Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009;123(6):e967-71.
-Nigrovic LE, Malley R, Agrawal D, Kuppermann N; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Low risk of bacterial meningitis in children with a positive enteroviral polymerase chain reaction test result. Clin Infect Dis. 2010;51(10):1221-2.
Respiratory Synctitial Virus & Serious Bacterial InfectionLevine DA, Kuppermann NNone-Levine DA, Platt SL, Dayan PS, Macias CG, Zorc JJ, Krief W, Schor J, Bank D, Fefferman N, Shaw KN, Kuppermann N for the Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections. Pediatrics. 2004;113(6):1728-34.
-Zorc JJ, Levine DA, Platt SL, Dayan PS, Macias CG, Krief W, Schor J, Bank D, Shaw KN, Kuppermann for the Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Clinical and demographic factors associated with urinary tract infection in young febrile infants. Pediatrics. 2005;116(3):644-8.
-Krief WI, Levine DA, Platt SL, Macias CG, Dayan PS, Zorc JJ, Feffermann N, Kuppermann N for Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Influenza virus infection and the risk of serious bacterial infections in young febrile infants. Pediatrics. 2009;124(1):30-9.
-Shah S, Zorc J, Levine D, Platt S and Kuppermann N. Sterile Cerebrospinal Fluid Pleocytosis in Young Infants with Urinary Tract Infection. J Pediatr 2008;153:290-2.
Diabetic KetoacidosisGlaser N, Kuppermann NAcademic Pediatric Association $7,150 / Children's Miracle Network $6,600-Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N for the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. N Engl J Med. 2001. 25;344(4):264-9.
Supraventricular TachycardiaLosek JDNone-Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N; American Academy of Pediatrics. The Pediatric Emergency Medicine Collaborative Research Committee. Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema. J Pediatr 2002; 141(6):793-7.
Blunt traumaDowd MDNone- Dowd MD, Krug S for the Pediatric Emergency Medicine Collaborative Research Committee: Working Group on Blunt Cardiac Injury. Pediatric blunt cardiac injury: epidemiology, clinical features, and diagnosis. J Trauma Injury Infect Crit Car. 1996; 40(1):61-7.
Physician WorkloadLosek JDNone-Losek JD for the Pediatric Emergency Medicine Collaborative Research Committee. Characteristics, workload, and job satisfaction of attending physicians from pediatric emergency medicine fellowship programs. Pediatr Emerg Car. 1994; 10(5):256-9.

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