PEMCRC Projects & Publications

Posted on Posted in PEMCRC Research Output
PEM CRC Projects and Publications
PEM Fellow Research Michelson Mistry Michelson KA, NIgrovic LE, Nagler J, McAneney CM, Mistry RD; Survey Committee of the Pediatric Emergency Medicine Collaborative Research Committee.  Research Interest in Pediatric Emergency Medicine Fellows. Pediatr Emerg Care 2017 Mar 13. [ePub].
Project PI & Mentor(s) Funding Publications
Completed Projects
Workload Losek None Losek JD for the Pediatric Emergency Medicine Collaborative Research Committee. Characteristics, workload, and job satisfaction of attending physicians from pediatric emergency medicine fellowship programs. Pediatr Emerg Car. 1994; 10(5):256-9.
Blunt chest trauma Dowd None Dowd MD, Krug S for the Pediatric Emergency Medicine Collaborative Research Committee: Working Group on Blunt Cardiac Injury. Pediatric blunt cardiac injury: epidemiology, clinical features, and diagnosis. J Trauma Injury Infect Crit Car. 1996; 40(1):61-7.
SVT Losek None Losek JD, Endom E, Dietrich A, Stewart G, Zempsky W, Smith K for the Pediatric Emergency Medicine Collaborative Research Committee. Adenosine and pediatric supraventricular tachycardia in the emergency department: multicenter study and review. Ann Emerg Med. 1999; 33(2):185-91.
Risk of admission Chamberlain None Chamberlain JM, Patel KM, Pollack MM, Brayer A, Macias CG, Okada P, Schunk JE for the Collaborative Research Committee of the Emergency Medicine Section of the American Academy of Pediatrics. Recalibration of the pediatric risk of admission score using a multi-institutional sample. Ann Emerg Med 2004;43(4):461-468.
DKA Glaser Kuppermann APA Special Projects Grant $7,150 Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. N Engl J Med. 2001. 25;344(4):264-9.
Children’s Miracle Network 6,600 Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N; American Academy of Pediatrics. The Pediatric Emergency Medicine Collaborative Research Committee. Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema. J Pediatr 2002; 141(6):793-7.
RSV-SBI Levine Kuppermann Levine DA, Platt SL, Dayan PS, Macias CG, Zorc JJ, Krief W, Schor J, Bank D, Fefferman N, Shaw KN, Kuppermann N; Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.
Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections. Pediatrics. 2004;113(6):1728-34.
Zorc JJ, Levine DA, Platt SL, Dayan PS, Macias CG, Krief W, Schor J, Bank D, Shaw KN, Kuppermann N; Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Clinical and demographic factors associated with urinary tract infection in young febrile infants. Pediatrics. 2005;116(3):644-8.
Krief WI, Levine DA, Platt SL, Macias CG, Dayan PS, Zorc JJ, Feffermann N, Kuppermann N; Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Influenza virus infection and the risk of serious bacterial infections in young febrile infants. Pediatrics. 2009;124(1):30-9.
Shah S, Zorc J, Levine D, Platt S and Kuppermann N. Sterile Cerebrospinal Fluid Pleocytosis in Young Infants with Urinary Tract Infection. J Pediatr 2008;153:290-2.
Meningitis Nigrovic Kuppermann Malley APA Young Investigator Grant 10,000 Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kanegaye JT, Malley R; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007;297(1):52-60.
Nigrovic LE, Kuppermann N, Malley R; Bacterial Meningitis Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.   Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era. Acad Emerg Med. 2008;15(6):522-8.
Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee. Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis. Pediatrics. 2008;122(4):726-30.
Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee. Pediatrics. 2009;123(6):e967-71.
Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N; American Academy of Pediatrics, Pediatric Emergency Medicine Collaborative Research Committee. Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009;123(6):e967-71.
Nigrovic LE, Malley R, Agrawal D, Kuppermann N; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Low risk of bacterial meningitis in children with a positive enteroviral polymerase chain reaction test result. Clin Infect Dis. 2010;51(10):1221-2.
UTI Schnadower Dayan Kuppermann None Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS; American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee. Febrile infants with urinary tract infections at very low risk for adverse events and bacteremia. Pediatrics. 2010;126(6):1074-83.
Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS; Sterile cerebrospinal fluid pleocytosis in young febrile infants with urinary tract infections. Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Arch Pediatr Adolesc Med. 2011;165(7):635-41.
Schnadower D, Kuppermann N, Macias CG, Freedman SB, Agrawal D, Mao J, Dayan PS for the American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee UTI Study Group. Outpatient management of young febrile infants with urinary tract infections. Pediatr Emerg Care. 2014 Sep;30(9):591-7.
Lubell, Schnadower, Kuppermann, Agrawal, Freedman, Dayan for the PEMCRC UTI study group: Comparison of Febrile Infants with Enterococcal and Gram-Negative Urinary Tract Infections. Pediatr Infecti Dis J. 2016, in press.
Appendicitis Kharbanda Dayan 10,000 Columbia Internal Grant Kharbanda AB, Stevenson MD, Macias CG, Sinclair K, Dudley NC, Bennett J, Bajaj L, Mittal MK, Huang C, Bachur RG, Dayan PS; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Interrater reliability of clinical findings in children with possible appendicitis. Pediatrics. 2012;129(4):695-700.
Bachur RG, Dayan PS, Bajaj L, Macias CG, Mittal MK, Stevenson MD, Dudley NC, Sinclair K, Bennett J, Monuteaux MC, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. The effect of abdominal pain duration on the accuracy of diagnostic imaging for pediatric appendicitis. Ann Emerg Med. 2012;60(5):582-590.
Kharbanda AB, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bachur RG, Bennett JE, Sinclair K, Huang C, Dayan PS; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Validation and refinement of a prediction rule to identify children at low risk for acute appendicitis. Arch Pediatr Adolesc Med. 2012;166(8):738-44.
Mittal MK, Dayan PS, Macias CG, Bachur RG, Bennett J, Dudley NC, Bajaj L, Sinclair K, Stevenson MD, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Performance of ultrasound in the diagnosis of appendicitis in children in a multicenter cohort.   Acad Emerg Med. 2013;20(7):697-702.
Levas MN, Dayan PS, Mittal MK, Stevenson MD, Bachur RG, Dudley NC, Bajaj L, Macias CG, Bennett J, Dowd MD, Thomas AJ, Kharbanda AB; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Effect of Hispanic ethnicity and language barriers on appendiceal perforation rates and imaging in children. J Pediatr. 2014;164(6):1286-91.
Bachur RG, Dayan PS, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bennett J, Sinclair K, Monuteaux MC, Kharbanda AB. The Influence of Age on the Diagnostic Performance of White Blood Cell Count and Absolute Neutrophil Count in Suspected Pediatric Appendicitis. Acad Emerg Med. 2016 Nov;23(11):1235-1242.
Kharbanda AB, Monuteaux MC, Bachur RG, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bennett JE, Sinclair K, Dayan PS; Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. A Clinical Score to predict Appendicitis in Older Male Children. Acad Pediatr 2016 Nov 24.
Active Projects
HSV Cruz    Freedman Nigrovic None Cruz A, Freedman S, Kulik D, Fleming A, Thomson J, Schnadower D, Garro A, Pruitt C, Balamuth F, Aronson P, Uspal N, Lyons T, Ishimine P, Bradin S, Grether-Jones K, Miller A, Louie L, Shah S, Nigrovic L, for the Pediatric Emergency Medicine Collaborative Research Committee (PEM-CRC) HSV Study Group. HSV in infants <= 60 days presenting for emergency department evaluation. Platform 2605, EM Multicenter research, Baltimore Convention Center Room 339/340 Sunday, 5/1, 1:45
Thomson J, Cruz A, Nigrovic L, Freedman S, Garro A, Ishimine P, Kulik D, Uspal N, Grether-Jones K, Miller A, Shah SS, for the Pediatric Emergency Medicine Collaborative Research Committee (PEM-CRC) HSV Study Group. Concomitant Bacterial Meningitis in Infants with Urinary Tract Infection.  Poster Session 4132 (PEM: UTI) Tuesday, 5/3, 730-930am.
Lyons TW, Cruz AT, Freedman SB, Numen MI, Balamuth F, Mistry R, Mahajan P, Aronson PL, Thomson JE, Pruitt CM, Shah SS, Nigrovic LE for the Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus (HSV) Study Group. Interpretation of cerebrospinal fluid white blood cell counts in young infants with a traumatic lumbar puncture. Ann of Emerg Med. 2017;69(5):622-31.
Thomson J, Cruz AT, Nigrovic LE, Freedman SB, Garro AC, Ishimine PT, Kulik DM, Uspal NG, Grether-Jones KL, Miller AS, Schnadower D, Shah SS, for the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC) HSV Study Group. Concomitant Bacterial Meningitis in Infants with Urinary Tract Infection. Pediatr Infect Dis J. 2017, in press.
Fusobacterium bacteremia Curfman Schnadower None Curfman, Burnham, Hayes, Schnadower for the PEMCRC Fusobacterium study group: Pediatric Anaerobic Blood Culture Practices in Developed Countries. PAS 2016 Baltimore. Poster session (PEM:ID) Saturday 4/30/2016, 1:30-3:00pm.
HUS McKee Schnadower None Recruiting sites
Neonatal Omphalitis Kaplan Bajaj None Protocol Initiation
Poisonings Mintegi PERN Mintegi S, Azkunaga B, Prego J, Qureshi N, Dalziel SR, Arana-Arri E, Acedo Y, Martinez-Indart L, Urkaregi A, Salmon N, Benito J, Kuppermann N; Pediatric Emergency Research Networks (PERN) Poisoning Working Group. International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. Pediatr Emerg Care. 2017 Jan 24. doi: 10.1097/PEC.0000000000001031. [Epub ahead of print]
Psychosocial Care Alisic PERN Alisic E, Hoysted C, Kassam-Adams N, Landolt MA, Curtis S, Kharbanda AB, Lyttle MD, Parri N, Stanley R, Babl FE; Pediatric Emergency Research Canada (PERC).; Pediatric Emergency Medicine Collaborative Research Committee of American Academy of Pediatrics (PEMCRC).; Pediatric Emergency Research in United Kingdom and Ireland (PERUKI).; Research in European Pediatric Emergency Medicine (REPEM).; Pediatric Emergency Care Applied Research Network (PECARN).; Pediatric Research in Emergency Departments International Collaborative (PREDICT).; Pediatric Emergency Research Networks (PERN). Psychosocial Care for Injured Children: Worldwide Survey among Hospital Emergency Department Staff. J Pediatr. 2016 Mar;170:227-33.e1-6

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